Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties: Case Study—Hypromellose (HPMC)

Journal article

Peer reviewed

P. Zarmpi, T. Flanagan, E. Meehan, J. Mann and N. Fotaki

The AAPS journal, Vol.22(2), p.49

18/02/2020

PMID: 32072317

Abstract

drug solubility

excipient variability

HPMC

physicochemical properties

viscosity

url

https://doi.org/10.1208/s12248-019-0411-1View

Published (Version of record) Open

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Title: Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties: Case Study—Hypromellose (HPMC)
Creators: P. Zarmpi - University of Bath
T. Flanagan - UCB Pharma (Belgium)
E. Meehan - AstraZeneca (United Kingdom)
J. Mann - AstraZeneca (United Kingdom)
N. Fotaki - University of Bath
Publication Details: The AAPS journal, Vol.22(2), p.49
Publication Date: 18/02/2020
Grant note: University of Bath (501100000835)
Identifiers: 991110183402346; WOS:000514799400001
Academic Unit: School of Chemistry & Chemical Engineering
Language: English
Resource Type: Journal article