A duplexed phenotypic screen for the simultaneous detection of inhibitors of the molecular chaperone heat shock protein 90 and modulators of cellular acetylation

A Hardcastle; P Tomlin; C Norris; J Richards; M Cordwell; K Boxall; M Rowlands; K Jones; I Collins; E McDonald; P Workman; W Aherne

doi:10.1158/1535-7163.MCT-06-0496

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A duplexed phenotypic screen for the simultaneous detection of inhibitors of the molecular chaperone heat shock protein 90 and modulators of cellular acetylation

Journal article

Peer reviewed

A duplexed phenotypic screen for the simultaneous detection of inhibitors of the molecular chaperone heat shock protein 90 and modulators of cellular acetylation

A Hardcastle, P Tomlin, C Norris, J Richards, M Cordwell, K Boxall, M Rowlands, K Jones, I Collins, E McDonald, …

MOLECULAR CANCER THERAPEUTICS, Vol.6(3), pp.1112-1122

01/03/2007

DOI: https://doi.org/10.1158/1535-7163.MCT-06-0496

Abstract

Science & Technology

Life Sciences & Biomedicine

Oncology

ONCOLOGY

HISTONE-DEACETYLASE INHIBITORS

SIGNAL-TRANSDUCTION

CRYSTAL-STRUCTURE

ATPASE ACTIVITY

GLUCOCORTICOID-RECEPTOR

BIOLOGICAL EVALUATION

CANCER THERAPEUTICS

ANTITUMOR QUINOLS

HSP90 INHIBITORS

IDENTIFICATION

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Title: A duplexed phenotypic screen for the simultaneous detection of inhibitors of the molecular chaperone heat shock protein 90 and modulators of cellular acetylation
Creators: A Hardcastle
P Tomlin
C Norris
J Richards
M Cordwell
K Boxall
M Rowlands
K Jones
I Collins
E McDonald
P Workman
W Aherne
Publication Details: MOLECULAR CANCER THERAPEUTICS, Vol.6(3), pp.1112-1122
Publisher: AMER ASSOC CANCER RESEARCH
Date published: 01/03/2007
Date submitted: 17/05/2017
Identifiers: 99514173002346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

A duplexed phenotypic screen for the simultaneous detection of inhibitors of the molecular chaperone heat shock protein 90 and modulators of cellular acetylation

Abstract

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