Abstract
As cancer treatment with hadrons becomes more and more widespread, the limitations of predicting their radiobiological effect via the current clinical approach is becoming more evident. Microdosimetry provides a stochastic approach more apt at describing hadron interactions than classical dosimetry. In this work a systematic Monte Carlo study is carried out for the purpose of standardisation and production of a preliminary uncertainty budget, for future use in clinics. Limitations of the Microdosimetric-Kinetic Model in predicting a radiobiological outcome are discussed. Lastly, a method to incorporate microdosimetry into clinical treatment planning is proposed.