The incidence of childhood cancer in the UK has increased by approximately 8–15% since the 1990s, with around 1,900 new cases diagnosed each year in children and young people (CYP) aged 0–14 years. Despite advances in treatment and improved survival rates, paediatric cancer remains the leading cause of disease-related death in CYP in the UK. The psychosocial impact of cancer can be profound and enduring, often extending beyond the completion of treatment, that affect not only the child but the entire family system. Despite these significant possible impacts there is inconsistent and limited support.

Part one of this portfolio presents a qualitative empirical study exploring the experiences of CYP and parents following the end of cancer treatment (EOT), a transitional period that has received limited attention in the literature, particularly within the UK. Using Interpretative Phenomenological Analysis (IPA), this study captures the complex emotional, physical, and relational challenges encountered by families following the EOT, a time often presumed to signify closure. Part two presents a systematic review of qualitative studies exploring the experiences of siblings of CYP with cancer. This review indicates that siblings experience a shattering of normality, emotional turmoil, feelings of invisibility, and for some, resilience and growth. However, siblings remain largely unacknowledged within services.

In its entirety, this thesis aims to provide insight and awareness into the experience of CYP with cancer and their families, across the illness trajectory. It outlines clinical and research implications with the hope that this could help to improve the support of CYP with cancer, parents and siblings.