Cortical blood flow imaging of mouse stroke model by high-speed Spectral OCT

Ireneusz Grulkowski; Grzegorz Wilczynski; Danuta Bukowska; Maciej Szkulmowski; Jakub Wlodarczyk; Karol Karnowski; Daniel Ruminski; Andrzej Kowalczyk; Maciej Wojtkowski; DANUTA SAMPSON

doi:10.1117/12.875212

Conference proceeding

Cortical blood flow imaging of mouse stroke model by high-speed Spectral OCT

Ireneusz Grulkowski, Grzegorz Wilczynski, Danuta Bukowska, Maciej Szkulmowski, Jakub Wlodarczyk, Karol Karnowski, Daniel Ruminski, Andrzej Kowalczyk, Maciej Wojtkowski and DANUTA SAMPSON

PHOTONIC THERAPEUTICS AND DIAGNOSTICS VII, Vol.7883(1), pp.788342-788347

Proceedings of SPIE

01/01/2011

DOI: https://doi.org/10.1117/12.875212

Abstract

Biophysics

Life Sciences & Biomedicine

Optics

Physical Sciences

Physics

Physics, Applied

Radiology, Nuclear Medicine & Medical Imaging

Science & Technology

We have developed and applied a high-speed Spectral OCT system to image small animal brains. OCT imaging with high spatial resolution and application of multi-parameter approach enabled cortical blood flow visualization. We imaged the brain vascular network of an anesthetized mouse stroke model. We demonstrated the impact of induced stroke on the brain vasculature. The preliminary studies have revealed local ischemia in the areas of the stroke.

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Title: Cortical blood flow imaging of mouse stroke model by high-speed Spectral OCT
Creators: Ireneusz Grulkowski - Nicolaus Copernicus University
Grzegorz Wilczynski - Instytut Biologii Doświadczalnej im. Marcelego Nenckiego
Danuta Bukowska - Nicolaus Copernicus University
Maciej Szkulmowski - Nicolaus Copernicus University
Jakub Wlodarczyk - Instytut Biologii Doświadczalnej im. Marcelego Nenckiego
Karol Karnowski - Nicolaus Copernicus University
Daniel Ruminski - Nicolaus Copernicus University
Andrzej Kowalczyk - Nicolaus Copernicus University
Maciej Wojtkowski - Nicolaus Copernicus University
DANUTA SAMPSON - Department of Electrical and Electronic Engineering
Contributors: N Kollias (Editor)
B Choi (Editor)
H Zeng (Editor)
H W Kang (Editor)
B E Knudsen (Editor)
BJF Wong (Editor)
JFR Ilgner (Editor)
K W Gregory (Editor)
G J Tearney (Editor)
L Marcu (Editor)
H Hirschberg (Editor)
S J Madsen (Editor)
A Mandelis (Editor)
A MahadevanJansen (Editor)
E D Jansen (Editor)
Publication Details: PHOTONIC THERAPEUTICS AND DIAGNOSTICS VII, Vol.7883(1), pp.788342-788347
Series: Proceedings of SPIE
Publisher: Spie-Int Soc Optical Engineering
Number of pages: 7
Date published: 01/01/2011
Grant note: Foundation for Polish Science EURYI-01/2008-PL / EuroHORCs-European Science Foundation EURYI; European Science Foundation (ESF) 2076/B/H03/2009/37 / Polish Ministry for Science and Higher Education; Ministry of Science and Higher Education, Poland
Identifiers: 99783404702346
Academic Unit: School of Computer Science and Electronic Engineering
Language: English
Resource Type: Conference proceeding

Cortical blood flow imaging of mouse stroke model by high-speed Spectral OCT

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