Abstract
Symptoms due to documented spontaneous hypoglycemia are an unusual consequence of many different rare diseases and are sometimes the primary reason for a patient seeking medical help. In a minority of patients no pathological cause can be found to account for the hypoglycemia and no specific curative or palliative therapy can be instituted. A small group of patients, among these, only experience symptoms 2–5h after eating a meal associated with low blood glucose levels. They may benefit from eating small, frequent, slowly absorbed carbohydrate rich meals.