Abstract
Punctate inner choroidopathy is an uncommon posterior multifocal chorioretinopathy first described by Watzke et al. (1984). It is character ized by the presence of small, focal, yellow lesions at the posterior pole occurring at the level of the inner choroid/retinal pigment epithelium in the absence of vitreous inflammation. It usually affects young, myopic females (who may also be fair haired with blue- or light-colored irides). The usual presenting symptoms include blurred vision, scotomata, and/or photopsia. These usually occur due secondary to inflammatory foci at the time of presentation, but can be caused by choroidal neovascularization (CNV) complicating the inflammatory focus or by scarring consequent to the inflammation. Despite having such a distinct clinical phenotype, there remains some controversy as to whether this disease simply represents part of a larger spectrum of chorioretinal disorders of unknown origin, including idiopathic multifocal choroiditis (MFC), the white dot syndrome (WDS) spectrum, and idiopathic or myopia-associated CNV formation. Although the majority of cases run a self-limited course, up to 69 % of eyes may develop CNV, and furthermore about half of eyes develop subretinal fibrosis with consequent visual loss often characterized by enlarging and new scotomata and in some cases further impairment of vision.